As someone who has spent the better part of 20 years with treatment-resistant depression, I’ve spent countless hours researching the “newest” advances in treatments.
For every new medication that came out, I was studying the mechanism of action to see if it was actually any different from the rest.
Sadly, most antidepressants fall into one or two categories and they are essentially all doing the same thing. I’ve tried them all, in various combinations, with little or no success.
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