November 9, 2022New research has identified 42 genes responsible for dyslexia, a language-based learning disorder, and confirmed its genetic link to attention deficit hyperactivity disorder (ADHD) in what is considered the largest genome-wide association study (GWAS) of dyslexia to date. Scientists from the Max Planck Institute for Psycholinguistics, QIMR Berghofer Medical Research Institute in Australia, the University of Edinburgh, and the U.S.-based consumer genetics company 23andMe, Inc.
conducted the study and published their findings in the journal Nature Genetics. 1“Family studies of dyslexia suggest heritability up to 70%, yet few convincing genetic markers have been found… meaning that this study changes our perspective on dyslexia genetics in a big way,” researchers said.Study participants drawn from the customer base of 23andMe, Inc.
included 51,800 adults with dyslexia (21,513 male, 30,287 female) and 1,087,070 (446,054 male, 641,016 female) without dyslexia. Their ages ranged from 18 to 110 years.DNA was extracted from saliva samples and genotyped on one of five genotyping platforms by the National Genetics Institute (NGI).
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