Donna Wilcock Donna Wilcock

Alzheimer’s Treatment With Antibodies Shows Promise in Clearing Plaques, Aiding Cognition

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psychcentral.com

Journal of Neuroinflammation, scientists focused on triggering a receptor expressed on myeloid cell-2 (TREM2) to reduce or prevent the development of the amyloid plaques and neurofibrillary tangles.

They believe creating an antibody could activate the cell receptor an opposite action that occurs when a mutation suppress the cell resulting in Alzheimer’s.“TREM2 was identified several years ago as a gene that, when there’s a mutation, significantly increases risk of Alzheimer’s disease.

The field thinks that this mutation reduces the function of the receptor, so we hypothesized that targeting TREM2 to increase its function might be a valid treatment for Alzheimer’s,” explained Dr.

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