Back in the day, I struggled with treatment-resistant depression. (This was likely due to the fact that what I had was actually bipolar II, but never mind that for now.) My psychiatrist prescribed me medication after medication, but none of them worked, or at least not for long.
We got into a seemingly endless spiral of trying one drug, adding another, weaning me off one drug and ramping up another, then another and another.
Some of them just plain didn’t work. Others had intolerable side effects, from vivid, horrible nightmares to making me feel like I was about to jump out of my skin.
Read more on themighty.com